Osam takes charge of his side for the final time this season, for games against Sweden, Austria and Turkey. They players will move on to Colin O'Brien's Under-17 side next season.
With three games in five days, Osam says the Development Tournament will be a taster for what's to come at Under-17 level.
"We're trying to replicate as close as possible to what the players will be dealing with next year at the Under-17 European Championships. They will be playing three games in five days in Sweden. It's as close as possible to what the players experience in tournament football.
"This is a culmination of everything we have done this season. We want to hand the best players over to Under-17 Head Coach Colin O'Brien for next season."
Osam's side begin their campaign on Sunday, May 18th against Sweden.
Republic of Ireland U16 Squad
Goalkeepers: Harry Halwax (Leixlip United), Dan Rose (Everton)
Defenders: Thomas Considine (Bohemians), Alex Dunne (Shamrock Rovers), James Furlong (Shamrock Rovers), Cian Kelly (Shamrock Rovers), Mazeed Ogungbo (Arsenal), Conrad Egan-Riley (Manchester City), Luke Turner (Shamrock Rovers)
Midfielders: Matt Healy (College Corinthians), Joe Hodge (Manchester City), Brandon Holt (St. Patrick's Athletic), Seamas Keogh (Sligo Rovers), Ronan McKinley (Derry City)
Forwards: Festy Ebosele (Bray Wanderers), Cillian Heaney (Sligo Rovers), Sean Kennedy (Tralee Dynamos), Sean McGrath (Limerick), Ayodeji Sotana (Manchester United), Conor Carty (Wolverhampton Wanderers)
UEFA Under-16 Development Tournament
Friday, May 18th: Sweden v Republic of Ireland, Lysekil, 6.30pm (5.30pm Irish time)
Sunday, May 20th: Republic of Ireland v Austria, Stenungsund, 3pm (2pm Irish time)
Tuesday, May 22nd: Turkey v Republic of Ireland, Munkedal, 11am (10am Irish time)