After earning a valuable point away to Serbia in their first Group D game, Ireland will host Georgia in Aviva Stadium on Thursday, October 6 before travelling to take on Moldova on Sunday, October 9 in Chisinau.
Included in the squad, for the first time, is Barnsley midfielder Conor Hourihane. The Cork native previously represented Ireland at underage level and has excelled in recent seasons in England's League One and Championship.
Goalkeeper Danny Rogers also earns a senior call-up, while Brighton & Hove Albion defender Shane Duffy is available following suspension.
Republic of Ireland Squad
Goalkeepers: Darren Randolph (West Ham United), Keiren Westwood (Sheffield Wednesday), Danny Rogers (Falkirk*)
Defenders: Seamus Coleman (Everton), Cyrus Christie, Richard Keogh, Alex Pearce (Derby County) Paul McShane (Reading), John O'Shea (Sunderland), Shane Duffy (Brighton & Hove Albion), Ciaran Clark (Newcastle United), Marc Wilson (Bournemouth), Stephen Ward (Burnley)
Midfielders: Aiden McGeady (Preston North End*), James McClean (West Bromwich Albion), Glenn Whelan (Stoke City), James McCarthy (Everton), Jeff Hendrick (Burnley), Stephen Quinn (Reading), David Meyler (Hull City), Conor Hourihane (Barnsley), Harry Arter (Bournemouth), Eunan O'Kane (Leeds United), Stephen Gleeson (Birmingham City), Callum O'Dowda (Bristol City), Robbie Brady, Wes Hoolahan (Norwich City), Anthony Pilkington (Cardiff City), Jonathan Hayes (Aberdeen)
Forwards: Shane Long (Southampton), Daryl Murphy (Newcastle United), Jonathan Walters (Stoke City), Kevin Doyle (Colorado Rapids)
*Indicates player is currently on loan